Job Listings

Join the Pack! A community with nearly 8,000 faculty and staff, and 30,000 students. NC State is one of the largest employers in North Carolina, offering a large range of career opportunities. Visit us at https://jobs.hr.ncsu.edu/.

Position Number: 00111795

Essential Job Duties:
We are looking for independent and highly motivated candidate to join our active and vibrant laboratory. The primary research focus of our laboratory is to study the host innate immune response as a barrier to cross-species retrovirus transmission in the non-human primates. We employ cutting-edge and novel, innovative approaches to study the replication of chimeric SIV/HIV viruses (SHIVs) in the macaque model of HIV-1 infection. Our laboratory is tackling a fundamental weakness in the HIV-1/AIDS field that affects all downstream aspects of HIV-1 pathogenesis, vaccine, and prevention research by developing more relevant SHIV/macaque models of HIV-1 infection.

The fully-funded project available for the postdoctoral fellow is to characterize the viral and host factors that drive selection, adaptation, and pathogenicity of HIV-1 and SHIVs (Sharma et al, PLOS Pathogens 2019, Vilmen et al, mBio 2022). The project will also focus on uncovering the molecular and mechanistic basis of adaptation of SHIVs to the macaque innate and adaptive immune responses (Sharma et al, J Med Primatol., 2015, Boyd et al, PLOS Pathogens 2016). This research project is highly interdisciplinary and built on the conceptual and technical skills from multiple unique fields of research - it combines expertise in HIV-1 transmission biology, translational immunology, and epidemiology with basic training in HIV-1 molecular virology, host cell biology and characterization of viral-host interactions.

Duties and Responsibilities:

• Research related to virology.
• 80% Research: Participates in experimental research focusing on studying host innate immune responses as a barrier to cross-species retrovirus transmission in the non-human primates; characterizes the viral and host factors that drive selection, adaptation, and pathogenicity of SHIVs in macaque cells ex vivo; uncover the molecular and mechanistic basis of adaptation of SHIVs to the macaque innate and adaptive immune responses; generates experimental data to support publications, PI's current active and future grant proposals and seek opportunities for independent funding.
• 15% Writing: Assists in the preparation of research reports, manuscripts, seminars, and presentations for ongoing research progress.
• 5% Other organizational and lab management duties as assigned.
• Successful completion of a University background check is required.
• Requires weekend, nights, and/or holiday hours

Departmental Required Skills:
n/a

Preferred Experience, Skills, Training/Education:
Past experience in HIV field strongly preferred.

Strong publication record.

Excellent writing, communication, and organizational skills.

Candidates with experience in protein purification and biochemical/biophysical characterization of Envelope glycoproteins and membranes are encouraged to apply.

Necessary Licenses or Certifications:
n/a

AA/EOE:
NC State University is an equal opportunity employer. All qualified applicants will receive equal opportunities for employment without regard to age, color, disability, gender identity, genetic information, national origin, race, religion, sex (including pregnancy), sexual orientation, and veteran status. The University encourages all qualified applicants, including protected veterans and individuals with disabilities, to apply. Individuals with disabilities requiring disability-related accommodations in the application and interview process are welcome to contact 919-513-0574 to speak with a representative of the Office of Equal Opportunity.

If you have general questions about the application process, you may contact Human Resources at (919) 515-2135 or workatncstate@ncsu.edu.

Final candidates are subject to criminal & sex offender background checks. Some vacancies also require credit or motor vehicle checks. Degree(s) must be obtained prior to start date in order to meet qualifications and receive credit.

NC State University participates in E-Verify. Federal law requires all employers to verify the identity and employment eligibility of all persons hired to work in the United States.

Department: 196001 - Department of Population Health and Pathobiology

Location: Raleigh, NC